Unnecessary polypharmacy for epilepsy.
نویسندگان
چکیده
A retrospective survey of 50 adult epileptic outpatients who were taking two anticonvulsants drugs showed that seizure control had improved in the six months after the introduction of the second drug in only 36%. When blood concentrations of the two anticonvulsants were subsequently measured improvement in seizure control was found to be significantly related to the presence of optimum blood concentrations of at least one drug. Much unnecessary polypharmacy in the treatment of epilepsy could be avoided by ensuring an optimum blood concentration of one drug before considering the addition of a second.
منابع مشابه
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BACKGROUND Polypharmacy is an important issue in primary care, yet few data are available concerning its prevalence, complications, and management in clinical medicine. The following case illustrates the clinical perils of polypharmacy and serves as a point for critical discussion. METHODS MEDLINE was searched, using the key word "polypharmacy," from 1994 to the present. A case report of poly...
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ورودعنوان ژورنال:
- British medical journal
دوره 1 6077 شماره
صفحات -
تاریخ انتشار 1977